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Disorders that occur in the nervous system affect millions of people every year. These disorders include trauma, vascular diseases, and immunological diseases of the nervous system. Many of these disorders produce changes in the blood-brain barrier. The goal of this program is to develop a sensor system that can monitor small changes in the blood-brain barrier.
Using state-of-the-art fiber optic technology, Foster-Miller is developing a sensor system that can monitor and map pressure changes along the blood-brain barrier in laboratory animals, as a model of the human blood-brain barrier. Our clinical partner, Tufts University School of Medicine, has implanted a prototype sensor into a laboratory rat. Following several weeks of post-operative recuperation, the sensor was activated and intra-cranial pressure measured. The sensor monitored changes in intracranial pressure throughout onset and progression of disease. Results of this program will permit medical professionals to identify a relationship between changes in intracranial pressure and the development of a neurological disease in an animals and humans.
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